Intersection of Climate and Environmental Change and Priority Health Outcomes Across the Life Course: Working Group 1 Report from the "Agriculture and Diet: Value Added for Nutrition, Translation, and Adaptation in a Global Ecology" (ADVANTAGE) Project.

An ecological approach examining multiple factors, internal (e.g., genetics and concurrent health status) and external (social determinants of diet/nutrition and physical environment), is essential for a comprehensive understanding of the interactions between climate and environmental change (CEC), nutrition, and health. We present evidence on the intersection of CEC and priority health outcomes across the life course. We include examples of observed impacts and future risks of exposure to weather variables (e.g., heat stress, humidity, and air quality) on health outcomes over the life course for particularly vulnerable groups relative to specific physiologic functions. For each life stage, we identify links between climate-related risks, undernutrition and overnutrition, micronutrient status, and health outcomes. From this review, we propose key knowledge gaps and research priorities.