The Creatine Kinase Response to Resistance Exercise: A Narrative Reanalysis and 12-Year Update

This research project is a formal narrative update and methodological reanalysis of our previously published milestone review, "The creatine kinase response to resistance exercise" (J Musculoskelet Neuronal Interact 2014; 14(1):68-77). Since its publication twelve years ago, advanced biotechnological diagnostics, complex strength training architectures, and novel ergogenic recovery strategies have completely redefined how exercise-induced muscle damage and hyperCKemia are understood and monitored in sports medicine and clinical biochemistry. The purpose of this project is to bridge the historical consensus established in 2014 with the contemporary scientific evidence up to 2026.