Abstract / Description
To establish an effective radiological risk stratification feature for metachronous metastasis of colon cancer. This retrospective, single-center study enrolled patients with stage II/III colon cancer who underwent curative surgery between December 2016 and September 2020. The ecological spatial characteristics of tumor habitats at the Class-level and Landscape-level were extracted by landscape pattern analysis. Univariate and multivariate COX regression analysis were used to determine the spatial characteristics related to metachronous metastasis and included in the prediction model, and the landscape score value was constructed to stratified the risk of metachronous metastasis. The predictive performance was evaluated using the time-dependent area under the ROC curve (AUC). Metachronous metastases occurred in 31 of 93 patients (median age, 61 years, [IQR, 51-65 years]). GYRATE-MD (HR: 1.67[95%CI: 1.14, 2.45]; P