Predictive efficacy of PASP combined with NT-proBNP for outcomes in pregnant women with severe cardiovascular disease: a single-centre retrospective observational study.

ObjectiveTo analyze maternal complications and pregnancy outcomes in pregnant women with severe cardiovascular disease (CVD), and explore the predictive value of pulmonary artery systolic pressure (PASP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) for these outcomes.MethodA retrospective observational study was conducted on pregnant women with severe CVD who were admitted to our hospital between December 2019 to August 2025. Demographic data, delivery mode, laboratory and imaging examination results, and post-partum follow-up data were collected. The primary outcome was CVD-related readmission or death during follow-up.ResultsA total of 158 patients (168 pregnancies) were included, with median follow-up of 1.8 (interquartile range 3.0) years. Among them, 86 cases achieved successful delivering, including 14 vaginal deliveries and 72 cesarean sections. Compared with the PASP