Abstract / Description
BackgroundThis study aimed to analyze epidemiological characteristics, clinical manifestations, and socio- environmental risk factors of viral-mycoplasma mixed respiratory infections in children presenting at fever clinics, providing evidence for clinical decision-making.MethodsIn this cross-sectional study, we analyzed clinical data from 132 pediatric patients with respiratory co-infections confirmed by direct immunofluorescence assay at the Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine (May 1, 2023 - April 30, 2024). Data collection included demographic characteristics, clinical symptoms, laboratory results, and pathogen profiles. Social behaviors and environmental factors were also evaluated. An age- and season-matched comparison group of 185 children with single respiratory infections was included. Statistical analyses involved t-tests, χ² tests, and multivariate logistic regression.ResultsThe majority of patients were aged 4-9 years (75.76%), with a male predominance (64.39%). Adenovirus was the most frequently detected pathogen (100 cases) and demonstrated the highest co-infection rate with Mycoplasma pneumoniae. Cases were primarily concentrated in the main urban area of Fuzhou City, notably in Jin'an (38 cases) and Gulou (34 cases) districts. The co-infection group had a significantly longer duration of fever than the single infection group (P