Abstract / Description
OBJECTIVE: To investigate the clinical characteristics and risk factors of invasive pulmonary aspergillosis (IPA) in patients with severe fever with thrombocytopenia syndrome (SFTS). METHODS: We conducted a retrospective analysis of 136 SFTS patients hospitalized at Zhongnan Hospital of Wuhan University between January 2017 and May 2024. Patients were stratified into IPA (n = 33) and non-IPA (n = 103) groups. Demographics, comorbidities, laboratory parameters, interventions, and outcomes were compared. Univariate and multivariate analyses were employed to evaluate the influencing factors, and Kaplan-Meier curves were utilized to assess survival outcomes. RESULTS: Compared to the non-IPA group, the IPA group was associated with significantly higher rates of severe disease (93.94% vs. 43.69%, P