Clinical characteristics, co-detection patterns and prognostic risk factors of human metapneumovirus infection in children: a retrospective study.

ObjectiveTo investigate clinical characteristics, co-detection patterns, and prognostic risk factors of human metapneumovirus (hMPV) infection in children.MethodsRetrospective study of 621 children with laboratory-detected hMPV infection. Clinical data, laboratory indicators, and co-detection status were analyzed. Multivariate logistic regression identified independent risk factors for severe pneumonia.ResultsMedian age was 3.50 years (IQR 1.75-4.75). Of 621 patients, 399 (64.3%) had Single-detection and 222 (35.7%) co-detection, with viral-viral co-detection dominant (68.9%) and rhinovirus the most common co-pathogen (39.6%). Only platelet count and aspartate aminotransferase differed significantly between groups (both P