Clinical Accuracy and Safety Concerns Following GPT-5 Public Demonstration in Cancer Care.

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Europe PMCPublished 2025Cancer & OncologyCancer Biology & Genetics
Journal
Journal of medical systems
Record source
Europe PMC Research Library

Abstract / Description

OpenAI's GPT-5 demonstration showed a patient uploading pathology reports to guide treatment decisions, though privacy implications were not addressed. We evaluated GPT-5 against 100 gastrointestinal oncology cases with tumor-board validation and found identical 85% concordance to GPT-4o, contradicting superiority claims. We recommend mandatory accuracy disclosures and regulatory oversight for AI health demonstrations to protect patient safety and privacy.
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