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Alterations in submaximal cardiopulmonary indicators in CVD patients participating in APBCRE-a comprehensive CPET-based study.

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Europe PMCPublished 2026Medicine & Clinical ResearchDisease Diagnosis & Prevention
Journal
Frontiers in cardiovascular medicine
Record source
Europe PMC Research Library

Abstract / Description

ObjectiveThis study aims to evaluate the clinical efficacy of a one-month Adaptive Postural Balance Cardiac Rehabilitation (APBCRE) program for patients with cardiovascular disease (CVD) using cardiopulmonary exercise testing (CPET), and to assess the validity of the oxygen uptake efficiency slope (OUES) as a measure of cardiopulmonary rehabilitation outcomes.DesignThe study implemented a one-month exercise rehabilitation program consisting of 12 sessions, held three times a week for 50-70β€…min each. All sessions were conducted on a one-on-one basis, with each patient receiving direct supervision throughout the program from certified cardiac rehabilitation nurses and physical therapists. A CPET test was administered by the same therapist before and after the program, and exercise instruction was provided prior to each test.ResultParticipants were stratified into two age groups for analysis. After completing the rehabilitation program, significant improvements were observed in WAT (56.86 ± 25.43 to 71.93 ± 26.64β€…w, p = 0.0009), VE at AT (29.64 ± 7.91 to 35.38 ± 12.22β€…mL/min/kg, p = 0.006), VO2 at AT (11.74 ± 3.20 to 13.79 ± 3.48β€…mL/min/kg, p = 0.002) and OUES [1,485.20 ± 377.54 to 1,610.60 ± 419.81β€…mL/(minΒ·L), p = 0.035]. The change in VO2 at AT was more pronounced than in VE at AT. The primary evaluation metrics were VO2 at AT and OUES, while secondary metrics included RER, HR, VE at AT, and VE/VCO2.ConclusionThe findings suggest that APBCRE is a potentially effective rehabilitation method for patients with cardiovascular disease, leading to significant improvements in exercise tolerance within one month. Furthermore, the OUES was found to be a potentially valuable indicator for assessing changes in cardiorespiratory fitness among young individuals during sports rehabilitation.
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